A Brooklyn female school teacher was charged with raping a male student and plying him with drugs and alcohol, police said Wednesday.

Sixth-grade humanities teacher Claudia Tillery, 42, was arrested at her three-bedroom home about 5:30 p.m. Tuesday.

She lives with her teenage daughter and young son, according to the building superintendent.

Tillery was charged with rape, unlawful dealing of drugs and alcohol to a child, sexual misconduct, sexual abuse and acting in a manner injurious to a child.

Officials said the victim is a 6th-grader at Stephen Decatur Middle School, in Bedford-Stuyvesant, Brooklyn, where Tillery began teaching in 1996. She earns $85,000 a year.

The boy, now 14, had been having a sexual relationship with Tillery since 2009 but decided to end it and come forward, sources said.

“I’m in shock,” said one mom whose daughter was in Tillery’s 6th-grade class last year.

“I still can’t believe this happened. Why would anyone do this? I’m ready to pull my kids out of the school. When your own child is affected by something like this, it’s scary.”

NYPD investigators questioned students, who described Claudia Tillery as a strict and serious teacher.

“I like her. All the kids liked her. She’s a good teacher. She was a pretty lady,” said an eighth-grader who was taught by Tillery two years ago.

“She was serious in class. I’m surprised that this happened.”

Tillery attended Edward R. Murrow High School in Brooklyn, and Central State University in Ohio, according to her Facebook page.

She has been removed from the classroom, pending the outcome of the criminal case, a Department of Education spokeswoman said.

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